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Latest Articles

Making Cells Burn More Calories β€” The Return of Mitochondrial Uncouplers
Cellular Aging Β· 6 min read

Making Cells Burn More Calories β€” The Return of Mitochondrial Uncouplers

Scientists developed safer compounds that tweak how mitochondria produce energy, making cells burn more calories while reducing oxidative stress.

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Eating Vitamin C Physically Changes Your Skin β€” From the Inside Out
5 min
Skin & Longevity

Eating Vitamin C Physically Changes Your Skin β€” From the Inside Out

New research shows dietary vitamin C reaches every layer of skin and works better than topical serums. Two kiwifruit a day thickened skin measurably in 8 weeks.

GlyNAC: The Two-Ingredient Supplement That Reverses Multiple Signs of Aging
7 min
Supplements

GlyNAC: The Two-Ingredient Supplement That Reverses Multiple Signs of Aging

A clinical trial showed that combining glycine and NAC restored glutathione, improved mitochondria, reduced inflammation, and reversed aging hallmarks in older adults.

Your Skin Is an Aging Clock β€” And Collagen Is the Key to Slowing It Down
7 min
Skin & Longevity

Your Skin Is an Aging Clock β€” And Collagen Is the Key to Slowing It Down

Skin aging mirrors what happens inside your entire body. Supporting collagen isn't just cosmetic β€” it's a whole-body longevity strategy.

The Longevity Evangelists: Who They Are and How Their Protocols Compare
12 min
Protocols

The Longevity Evangelists: Who They Are and How Their Protocols Compare

Bryan Johnson, Dave Asprey, Peter Attia, Rhonda Patrick, and David Sinclair β€” their protocols compared side by side with practical takeaways.

Creatine Isn't Just for Gym Bros β€” It Protects Your Brain
6 min
Supplements

Creatine Isn't Just for Gym Bros β€” It Protects Your Brain

Creatine is the most studied sports supplement in history. But new research shows it also protects against neurodegeneration, improves cognition, and may slow brain aging.

Omega-3s: The Anti-Inflammation Supplement That Actually Works
7 min
Supplements

Omega-3s: The Anti-Inflammation Supplement That Actually Works

Most anti-inflammatory supplements are overhyped. Omega-3 fatty acids are the exception β€” with massive trials proving cardiovascular, brain, and longevity benefits.

Magnesium: The Deficiency You Probably Have
6 min
Supplements

Magnesium: The Deficiency You Probably Have

Up to 50% of Americans don't get enough magnesium. This single mineral affects sleep, muscle function, blood pressure, insulin sensitivity, and over 300 enzymatic reactions.

Zone 2 Cardio: The Longevity Exercise That Feels Too Easy
7 min
Protocols

Zone 2 Cardio: The Longevity Exercise That Feels Too Easy

Peter Attia calls it the most important exercise for longevity. Zone 2 cardio builds mitochondria, burns fat, and predicts how long you'll live.

The Science of Sauna: How Heat Exposure Cuts Mortality by 40%
7 min
Protocols

The Science of Sauna: How Heat Exposure Cuts Mortality by 40%

Finnish studies following thousands of men for 20+ years found that regular sauna use dramatically reduces death from cardiovascular disease, stroke, and all causes.

Senolytics: The Drugs That Kill Your Body's Zombie Cells
7 min
Cellular Aging

Senolytics: The Drugs That Kill Your Body's Zombie Cells

Senescent "zombie" cells accumulate with age and poison their neighbors. A new class of drugs β€” senolytics β€” can selectively destroy them, with dramatic results in trials.

Rapamycin: The Most Promising Anti-Aging Drug Nobody's Taking
8 min
Cellular Aging

Rapamycin: The Most Promising Anti-Aging Drug Nobody's Taking

Originally an immunosuppressant from Easter Island soil, rapamycin extends lifespan in every organism tested. Low-dose protocols are now being studied in humans.

NAD+ Decline: Why Your Cells Run Out of Fuel After 40
8 min
Cellular Aging

NAD+ Decline: Why Your Cells Run Out of Fuel After 40

NAD+ is essential for energy production, DNA repair, and sirtuin activation. It drops dramatically with age. NMN and NR promise to restore it β€” but does the science hold up?

Sunscreen Is the Single Best Anti-Aging Product That Exists
6 min
Skin & Longevity

Sunscreen Is the Single Best Anti-Aging Product That Exists

The famous Australian twin studies proved it definitively: UV protection does more for skin aging than any cream, serum, or supplement combined.

Retinoids: The Only Topical With 50 Years of Anti-Aging Evidence
6 min
Skin & Longevity

Retinoids: The Only Topical With 50 Years of Anti-Aging Evidence

Tretinoin (prescription retinoid) is the most studied anti-aging topical in history. It stimulates collagen, speeds cell turnover, and reverses photoaging β€” with decades of proof.

The Rejuvenation Olympics: Inside the Competition to Age Backwards
10 min
Protocols

The Rejuvenation Olympics: Inside the Competition to Age Backwards

A global leaderboard where competitors race to slow their biological aging. Using epigenetic testing, the Rejuvenation Olympics ranks who's aging the slowest β€” and Bryan Johnson is winning.

Spermidine: The Autophagy Activator That Could Slow Aging
8 min
Supplements

Spermidine: The Autophagy Activator That Could Slow Aging

Found in wheat germ and aged cheese, spermidine triggers your cells' recycling system. Epidemiological data links higher intake to 5+ years of reduced mortality.

Urolithin A: Recycling Your Mitochondria for Longer Life
8 min
Supplements

Urolithin A: Recycling Your Mitochondria for Longer Life

Your gut bacteria should make it from pomegranates β€” but most people's can't. Urolithin A triggers mitophagy, and clinical trials show real muscle benefits in older adults.

Fisetin: The Strawberry Compound That Kills Zombie Cells
9 min
Supplements

Fisetin: The Strawberry Compound That Kills Zombie Cells

Senescent "zombie cells" accumulate with age and poison their neighbors. Fisetin emerged as the most potent natural senolytic in a screen of 10 flavonoids.

Ergothioneine: The "Longevity Vitamin" Hidden in Mushrooms
8 min
Supplements

Ergothioneine: The "Longevity Vitamin" Hidden in Mushrooms

Your body has a dedicated transporter for this amino acid it can't make. A renowned biochemist argues it should be classified as a vitamin β€” and its decline with age may drive disease.

Taurine: The Cheap Amino Acid That Extended Lifespan by 12%
8 min
Supplements

Taurine: The Cheap Amino Acid That Extended Lifespan by 12%

A landmark 2023 Science paper showed taurine deficiency drives aging β€” and supplementing it extended mouse lifespan by 10-12%. At 3 cents a day, it's the cheapest longevity bet.

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